Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.40 |
| ▸ | WEE1 | P30291 | 4/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 4/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527534 | 0.86 | KDR (0.41) | KDRCHEK1WEE1ABCG2STK10 | |
| SCHEMBL11529207 | 0.83 | GSK3B (0.42) | KDRCHEK1WEE1ABCG2STK10 | |
| SCHEMBL11717134 | 0.81 | KDM4E (0.43) | KDRSTK10SLKCDK2CDK4 | |
| SCHEMBL11717630 | 0.72 | GSK3B (0.38) | KDRSTK10SLKCDK2CDK4 | |
| SCHEMBL11718359 | 0.72 | EGFR (0.41) | STK10SLKCDK2CDK4CCND1 | |
| SCHEMBL11533447 | 0.70 | WEE1 (0.37) | CHEK1WEE1STK10SLKCDK2 | |
| SCHEMBL11712229 | 0.69 | MAOA (0.41) | KDRSTK10SLKCDK2CDK4 | |
| SCHEMBL11716003 | 0.69 | PTGER4 (0.39) | CHEK1WEE1CDK4CCND1GSK3B | |
| SCHEMBL11713383 | 0.69 | GSK3B (0.36) | KDRCHEK1WEE1CDK2CDK4 | |
| SCHEMBL384815 | 0.68 | TOP1 (0.55) | CHEK1WEE1STK10SLKCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139532-A | OPTICAL BRIGHTENERS FOR POLYESTERS AND THEIR BLENDS WITH COTTON | BASF AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |