Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CCND1 | P24385 | 3/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKCH | P24723 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 2/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717134 | 0.84 | KDM4E (0.43) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11712283 | 0.82 | CDK4 (0.40) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11712229 | 0.80 | MAOA (0.41) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11716003 | 0.80 | PTGER4 (0.39) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11712853 | 0.78 | PTGER4 (0.37) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11715487 | 0.77 | GSK3B (0.36) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11717398 | 0.77 | HPGD (0.41) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11722544 | 0.77 | PTGER4 (0.38) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11713383 | 0.77 | GSK3B (0.36) | GSK3BCDK4CCND1CDK5CDK5R1 | |
| SCHEMBL11709013 | 0.77 | ALDH1A1 (0.46) | GSK3BMEN1CCNB2CCNE2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |