SCHEMBL11527619

SCHEMBL11527619

CCC(=O)OCC1=CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
WRN Q14191 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11528557 0.88 NLRP3 (0.41) ALDH1A1
SCHEMBL11526931 0.78 SMN1; SMN2 (0.35) ALDH1A1
SCHEMBL11529890 0.75 ALDH1A1 (0.38) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL11528138 0.74 HSP90AB1 (0.36) ALDH1A1
SCHEMBL11526100 0.70 ALDH1A1 (0.34) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL28056713 0.62 ALDH1A1 (0.36) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL23706607 0.62
SCHEMBL7641621 0.62 ALDH1A1 (0.52) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL21711254 0.61 KDM4E (0.36) ALDH1A1HPGD
SCHEMBL22160477 0.60 ALDH1A1 (0.39) ALDH1A1CYP1A2HPGDCYP2C19BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4132750-A RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES SHOWA DENKO K.K. (JP) 1979-01-02 US disclosed
US-4080491-A CATALYST CONTAINS ORGANOMETALLIC COMPOUND AND THE REACTION PRODUCT OF TUNGSTEN OR MOLYBDENUM OXIDE AND A PHOSPHOROUS HALIDE OR OXYHALIDE SHOWA DENKO K.K. (JA) 1978-03-21 US disclosed
US-4028482-A LOW VISCOSITY POLYALKENAMER SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-06-07 US disclosed