SCHEMBL21711254

SCHEMBL21711254

COC(=O)C1=C[C@@H]2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.36
ALDH1A1 P00352 7/20 0.36
GAA P10253 7/20 0.36
HPGD P15428 6/20 0.36
CASP1 P29466 6/20 0.36
CASP7 P55210 6/20 0.36
HSD17B10 Q99714 6/20 0.36
TSHR P16473 3/20 0.36
ATM Q13315 2/20 0.36
GLA P06280 5/20 0.35
KCNH2 Q12809 1/20 0.35
TLR4 O00206 1/20 0.35
MAPK1 P28482 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
RCE1 Q9Y256 1/20 0.32
CA12 O43570 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4169291 1.00 KDM4E (0.36) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL18758051 0.84 KDM4E (0.32) KDM4EALDH1A1GAAHPGDCASP1
4-Vinylphenol SCHEMBL16736992 0.82 CA1 (0.36) ALDH1A1POLBMEN1KMT2ACA12
SCHEMBL18714029 0.81 KDM4E (0.30) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL11533080 0.81 CA12 (0.36) KDM4EALDH1A1GAAHSD17B10TSHR
SCHEMBL1831584 0.81 TSHR (0.38) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL8507944 0.79 CHRNB2 (0.31) ALDH1A1
SCHEMBL11525930 0.78 ALDH1A1 (0.41) KDM4EALDH1A1HPGDHSD17B10TSHR
SCHEMBL8911453 0.77 TLR4 (0.35) KDM4EALDH1A1GAAHPGDCASP1
SCHEMBL75668 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200050107-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 US disclosed