Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HNF4A | P41235 | 2/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528988 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPK1TDP1HNF4AACMSD | |
| SCHEMBL7075790 | 0.83 | ALDH1A1 (0.74) | ALDH1A1MAPK1TDP1CDC25BATM | |
| SCHEMBL11568765 | 0.80 | ACMSD (0.49) | ALDH1A1MAPK1TDP1HNF4AACMSD | |
| SCHEMBL11530588 | 0.80 | ACMSD (0.49) | ALDH1A1MAPK1TDP1HNF4AACMSD | |
| SCHEMBL11533689 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPK1TDP1ACMSDCDC25B | |
| SCHEMBL6422025 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HNF4AACMSDCDC25BATM | |
| SCHEMBL11536804 | 0.78 | PTPN1 (0.45) | ALDH1A1MAPK1TDP1HNF4AACMSD | |
| SCHEMBL11530033 | 0.78 | BCAT2 (0.46) | ALDH1A1MAPK1TDP1HNF4ACDC25B | |
| SCHEMBL11530381 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPK1TDP1CDC25BATM | |
| SCHEMBL27580030 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPK1TDP1CDC25BATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147728-A | Disubstituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4064176-A | Di-substituted meta-terphenyl compounds and resulting polymers | INSTITUT FRANCAIS DU PETROLE (FR) | 1977-12-20 | — | — | US | disclosed |