Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530298 | 0.84 | KMT2A (0.48) | KMT2AL3MBTL1OPRM1OPRL1HPGD | |
| SCHEMBL11530105 | 0.80 | GAA (0.48) | L3MBTL1HPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3065468 | 0.77 | IDO1 (0.42) | HPGDALDH1A1SMN1; SMN2LMNAPKM | |
| SCHEMBL8728754 | 0.76 | CYP2C19 (0.47) | HPGDLMNAPKMNPC1RAB9A | |
| SCHEMBL11527978 | 0.74 | OPRM1 (0.44) | KMT2AL3MBTL1OPRM1OPRL1HPGD | |
| SCHEMBL22559961 | 0.74 | ALDH1A1 (0.61) | KMT2AALDH1A1LMNANPC1RAB9A | |
| SCHEMBL27306094 | 0.74 | L3MBTL1 (0.54) | KMT2AL3MBTL1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL967460 | 0.72 | NPC1 (0.62) | KMT2AOPRM1OPRL1HPGDSMN1; SMN2 | |
| SCHEMBL11524885 | 0.72 | LMNA (0.47) | KMT2AL3MBTL1OPRM1OPRL1HPGD | |
| SCHEMBL11255144 | 0.71 | ALDH1A1 (0.40) | ALDH1A1LMNAGAAPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |