Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 3/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074978 | 0.86 | HNF4A (0.66) | HNF4APDK2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL3420505 | 0.85 | BCAT2 (0.57) | HNF4APDK2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL30505632 | 0.85 | BCAT2 (0.57) | HNF4APDK2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL28738496 | 0.84 | MAPT (0.50) | HNF4APDK2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL27539512 | 0.84 | BCAT2 (0.55) | HNF4APDK2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL28648733 | 0.83 | FABP4 (0.53) | HNF4APDK2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL8889664 | 0.83 | L3MBTL1 (0.49) | HNF4APDK2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL28817957 | 0.83 | HNF4A (0.51) | HNF4AL3MBTL1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL28217107 | 0.83 | SMN1; SMN2 (0.49) | HNF4APDK2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL5008897 | 0.82 | HNF4A (0.46) | HNF4AL3MBTL1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140770-A | Benzoylethers and processes for their production | A. NATTERMANN & CIE. GMBH (DE) | 1979-02-20 | — | — | US | disclosed |
| US-3984438-A | INSECTICIDES AND FIRE RETARDANTS | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |