Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.40 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428750 | 0.82 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2EPHX1ACHEMMP2 | |
| SCHEMBL11530181 | 0.81 | EPHX1 (0.48) | EPHX1ACHEMMP2TSHRHTT | |
| SCHEMBL176404 | 0.80 | ALDH1A1 (0.38) | — | |
| SCHEMBL3272590 | 0.78 | EPHX1 (0.45) | EPHX1ACHEMMP2TSHRHTT | |
| SCHEMBL11096312 | 0.77 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2EPHX1FAAHCASP2 | |
| SCHEMBL11561683 | 0.76 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2EPHX1FAAHCASP2 | |
| SCHEMBL7203269 | 0.76 | SMN1; SMN2 (0.42) | FAAHTSHRHTT | |
| SCHEMBL11444171 | 0.73 | EPHX1 (0.50) | ZDHHC20ZDHHC2EPHX1CASP2 | |
| SCHEMBL11337878 | 0.72 | FAAH (0.53) | ZDHHC20ZDHHC2EPHX1FAAHTSHR | |
| SCHEMBL11221492 | 0.72 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2EPHX1FAAHCASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |