Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457464 | 0.81 | LDHA (0.48) | LDHA | |
| SCHEMBL17050818 | 0.80 | MRGPRX4 (0.60) | MRGPRX4ENPP2RAB9ANPC1HPGD | |
| SCHEMBL11305903 | 0.79 | LDHA (0.71) | LDHAKMT2ACYP1A2CYP2C19PPARA | |
| SCHEMBL11308216 | 0.78 | MRGPRX4 (0.48) | MRGPRX4RAB9ANPC1HPGDSMN1; SMN2 | |
| Arildone SCHEMBL146967 | 0.77 | MRGPRX4 (0.47) | MRGPRX4HPGDMEN1KMT2AALDH1A1 | |
| Arildone SCHEMBL29807845 | 0.77 | MRGPRX4 (0.47) | MRGPRX4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11309550 | 0.77 | MRGPRX4 (0.47) | MRGPRX4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11546537 | 0.77 | MRGPRX4 (0.47) | MRGPRX4HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11527960 | 0.77 | NFE2L2 (0.44) | LDHACYP1A2 | |
| SCHEMBL11527964 | 0.77 | NFE2L2 (0.44) | LDHACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153719-A | Aromatic diketones | STERLING DRUG INC. (US) | 1979-05-08 | — | — | US | disclosed |