Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987611 | 0.83 | L3MBTL1 (0.73) | L3MBTL1LMNAALDH1A1MAPTTHRB | |
| SCHEMBL5433772 | 0.83 | L3MBTL1 (0.63) | L3MBTL1LMNAALDH1A1MAPTTHRB | |
| SCHEMBL11170994 | 0.81 | L3MBTL1 (0.61) | L3MBTL1LMNAALDH1A1MAPTTHRB | |
| SCHEMBL11423478 | 0.79 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL1276930 | 0.79 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL4603063 | 0.79 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL5458866 | 0.78 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL11529582 | 0.78 | L3MBTL1 (0.65) | L3MBTL1LMNAALDH1A1MAPTTHRB | |
| SCHEMBL966694 | 0.77 | MEN1 (0.69) | L3MBTL1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL28287200 | 0.76 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1MAPTTHRBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |