Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528334 | 0.83 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL7987611 | 0.81 | L3MBTL1 (0.73) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL11170994 | 0.80 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL4603063 | 0.78 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL1276930 | 0.78 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL11423478 | 0.78 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL4294745 | 0.78 | MEN1 (0.67) | L3MBTL1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL1024200 | 0.77 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL5458866 | 0.76 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1MAPTTHRBPKM | |
| SCHEMBL11529582 | 0.76 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1MAPTTHRBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220768-B2 | Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus | WYETH HOLDINGS CORP. (US) | 2007-05-22 | — | — | US | disclosed |