Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528355 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CYP3A4ALOX15TDP1MAPK1 | |
| SCHEMBL11761262 | 0.93 | ALDH1A1 (0.35) | ALDH1A1CYP3A4ALOX15TDP1MAPK1 | |
| SCHEMBL11527732 | 0.88 | MAPK1 (0.32) | ALDH1A1MAPK1 | |
| SCHEMBL11527735 | 0.88 | MAPK1 (0.32) | ALDH1A1MAPK1 | |
| SCHEMBL11600232 | 0.85 | MAPK1 (0.34) | ALDH1A1MAPK1POLBL3MBTL1HCAR2 | |
| SCHEMBL11600228 | 0.85 | MAPK1 (0.34) | ALDH1A1MAPK1POLBL3MBTL1HCAR2 | |
| SCHEMBL11529324 | 0.85 | TRPA1 (0.35) | MAPK1POLB | |
| SCHEMBL11529331 | 0.85 | TRPA1 (0.35) | MAPK1POLB | |
| SCHEMBL11511502 | 0.84 | TRPA1 (0.41) | POLB | |
| SCHEMBL11511498 | 0.84 | TRPA1 (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161608-A | 11 Hydroxy methyl 11-deoxyprostaglandin E1 | AYERST, MCKENNA AND HARRISON LIMITED (CA) | 1979-07-17 | — | — | US | disclosed |
| US-4100343-A | 11-Deoxyprostaglandin derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-07-11 | — | — | US | disclosed |
| US-4092427-A | ANTICOAGULANTS, OXYTOCICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4089898-A | 11-Deoxyprostaglandin derivatives | AYERST, MCKENNA & HARRISON LTD. (CA) | 1978-05-16 | — | — | US | disclosed |
| US-4048329-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4036856-A | PROSTAGLANDINS | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-07-19 | — | — | US | disclosed |
| US-4007171-A | PROSTAGLANDIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
| US-4006136-A | Prostaglandin intermediates | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-02-01 | — | — | US | disclosed |