Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600228 | 1.00 | MAPK1 (0.34) | MAPK1LMNAALDH1A1HSD17B10POLB | |
| SCHEMBL11528347 | 0.85 | ALDH1A1 (0.38) | MAPK1ALDH1A1POLBHCAR2L3MBTL1 | |
| SCHEMBL11528355 | 0.85 | ALDH1A1 (0.38) | MAPK1ALDH1A1POLBHCAR2L3MBTL1 | |
| SCHEMBL11527735 | 0.83 | MAPK1 (0.32) | MAPK1ALDH1A1 | |
| SCHEMBL11527732 | 0.83 | MAPK1 (0.32) | MAPK1ALDH1A1 | |
| SCHEMBL11599820 | 0.81 | CYP4F2 (0.31) | — | |
| SCHEMBL11599824 | 0.81 | CYP4F2 (0.31) | — | |
| SCHEMBL11529324 | 0.80 | TRPA1 (0.35) | MAPK1POLBATM | |
| SCHEMBL11529331 | 0.80 | TRPA1 (0.35) | MAPK1POLBATM | |
| SCHEMBL11511502 | 0.79 | TRPA1 (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4007171-A | PROSTAGLANDIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-02-08 | — | — | US | claimed |
| US-4092427-A | ANTICOAGULANTS, OXYTOCICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4048329-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048328-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4007171-A | PROSTAGLANDIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |