Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527852 | 0.76 | EZH2 (0.41) | ALDH1A1L3MBTL1KDM4EGAAHPGD | |
| SCHEMBL1025172 | 0.74 | ALDH1A1 (0.66) | ALDH1A1TDP1L3MBTL1MAPTPOLB | |
| SCHEMBL27780197 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TDP1L3MBTL1KDM4ERXFP1 | |
| SCHEMBL11170777 | 0.69 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1RXFP1MAPT | |
| SCHEMBL24316347 | 0.68 | RXFP1 (0.40) | ALDH1A1TDP1L3MBTL1KDM4ERXFP1 | |
| SCHEMBL11531963 | 0.66 | TSHR (0.33) | ALDH1A1L3MBTL1KDM4EGAALMNA | |
| SCHEMBL2724245 | 0.65 | ALDH1A1 (0.38) | ALDH1A1TDP1L3MBTL1KDM4ERXFP1 | |
| SCHEMBL2723974 | 0.65 | ALDH1A1 (0.38) | ALDH1A1TDP1L3MBTL1RXFP1MAPT | |
| SCHEMBL17980826 | 0.64 | KDM4E (0.42) | ALDH1A1L3MBTL1KDM4EMAPTNPC1 | |
| SCHEMBL21955382 | 0.64 | KDM4E (0.42) | ALDH1A1L3MBTL1KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159202-A | PHOTOCOPYING | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |
| US-4145430-A | BETA-LACTAM COMPOUNDS, PREPARATION AND USE | BEECHAM GROUP LIMITED (GB) | 1979-03-20 | — | — | US | disclosed |