Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 8/20 | 0.41 |
| ▸ | EED | O75530 | 2/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.41 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528409 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL11531963 | 0.75 | TSHR (0.33) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL18455423 | 0.74 | EZH2 (0.39) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL11857804 | 0.73 | ALDH1A1 (0.35) | EZH2KDM4EALDH1A1MMP1MMP7 | |
| SCHEMBL17792554 | 0.71 | SETDB1 (0.38) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL11527449 | 0.71 | KMT2A (0.36) | KMT2A | |
| SCHEMBL207449 | 0.70 | MEN1 (0.41) | ALDH1A1CYP1A2L3MBTL1MMP13MEN1 | |
| SCHEMBL22017507 | 0.70 | KDM4E (0.40) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL15647981 | 0.69 | KDM4E (0.39) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2723976 | 0.68 | P2RX7 (0.40) | P2RX7KDM4EALDH1A1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159202-A | PHOTOCOPYING | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |