Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705146 | 0.87 | EZH2 (0.53) | EZH2GAAPOLBTSHRHTT | |
| SCHEMBL11533251 | 0.76 | L3MBTL1 (0.40) | EZH2GAAUSP2POLBTSHR | |
| SCHEMBL11530426 | 0.74 | EZH2 (0.47) | EZH2GAAPOLBTSHRHTT | |
| SCHEMBL2908330 | 0.72 | EZH2 (0.89) | EZH2POLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL11532347 | 0.71 | EZH2 (0.56) | EZH2GAAUSP2POLBTSHR | |
| SCHEMBL11526282 | 0.70 | L3MBTL1 (0.39) | EZH2GAAUSP2POLBKMT2A | |
| SCHEMBL11528566 | 0.70 | GAA (0.50) | EZH2GAAUSP2POLBTSHR | |
| SCHEMBL40016 | 0.70 | GAA (0.59) | EZH2GAAPOLBTSHRHTT | |
| SCHEMBL2048794 | 0.69 | TSHR (0.54) | GAAPOLBTSHRHTTKMT2A | |
| SCHEMBL4013088 | 0.69 | TSHR (0.54) | GAAPOLBTSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |