Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.83 |
| ▸ | GAA | P10253 | 7/20 | 0.83 |
| ▸ | MEN1 | O00255 | 6/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.83 |
| ▸ | PKM | P14618 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | RRM2 | P31350 | 1/20 | 0.46 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109703 | 0.91 | MAPT (1.00) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL11506844 | 0.83 | ALDH1A1 (0.89) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL28026099 | 0.82 | MAPT (0.59) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL7912825 | 0.82 | MAPK1 (0.70) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL11533820 | 0.79 | HCAR3 (0.68) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL11507400 | 0.78 | ALDH1A1 (0.79) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL230292 | 0.78 | TDP1 (1.00) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL31333098 | 0.78 | TDP1 (1.00) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL27844608 | 0.78 | MEN1 (0.74) | MAPTGAAMEN1KMT2AMAPK1 | |
| SCHEMBL11217415 | 0.77 | IDE (0.53) | MAPTGAAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145342-A | NITRO-DIPHENYLAMINO-AZO-PHENYL DYESTUFFS CONTAINING A POLYALKYENEOXY GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |