Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 12/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425306 | 0.86 | MAOB (0.70) | LMNAL3MBTL1MAOBALOX5PTGS1 | |
| SCHEMBL5004504 | 0.85 | ALOX15 (0.70) | LMNAL3MBTL1MAPK1CASP3SENP7 | |
| SCHEMBL7746 | 0.85 | ALOX15 (0.68) | LMNAL3MBTL1ALOX15 | |
| SCHEMBL12890389 | 0.84 | ELANE (0.50) | LMNAL3MBTL1MAPK1CASP3SENP7 | |
| SCHEMBL17364452 | 0.83 | PTGS2 (0.51) | LMNAL3MBTL1LTA4HPTGS2 | |
| SCHEMBL2955123 | 0.82 | HPGD (0.50) | L3MBTL1ALOX15 | |
| SCHEMBL7141666 | 0.82 | GPR174 (0.56) | LMNAL3MBTL1MAPK1CASP3SENP7 | |
| SCHEMBL7733929 | 0.81 | MAPT (0.66) | LMNACASP3SENP7SENP6ALOX15 | |
| SCHEMBL8225239 | 0.81 | SMN1; SMN2 (0.67) | L3MBTL1LTA4HMAOBALOX15PPARG | |
| SCHEMBL9787068 | 0.81 | LMNA (0.80) | LMNAL3MBTL1MAPK1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172146-A | Substituted phenyl derivatives | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |
| US-4069344-A | INSECTICIDAL SUBSTITUTED PHENYL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-01-17 | — | — | US | disclosed |