SCHEMBL4059532

SCHEMBL4059532

C=C(C)C(=O)OC(C)CCl

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.47
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 1/20 0.39
THRB P10828 1/20 0.35
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
GALR3 O60755 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2540758 0.82 TSHR (0.50) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL2544205 0.82 TSHR (0.50) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL1130699 0.80 TSHR (0.43) TSHRALDH1A1THRBHSD17B10TDP1
SCHEMBL15751663 0.80 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL2013862 0.80 TSHR (0.54) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL377956 0.80 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL33467 0.80 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL204713 0.80 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL15318827 0.80 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL1951992 0.78 TSHR (0.42) TSHRALDH1A1THRBHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586020-B2 Poly(organophosphazene) composition for biomaterials KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-11-19 US disclosed
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-01-03 US disclosed
EP-2540764-A2 Poly(organophosphazene) composition for biomaterials Korea Institute of Science and Technology (KR) 2013-01-02 EP disclosed
US-8313771-B2 Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-20 US disclosed
EP-1798252-B1 CROSSLINKED FLUOROCOPOLYMER MOLDINGS UNIMATEC CO LTD (JP) 2009-10-21 EP disclosed
US-20090023863-A1 CROSS-LINKED FLUORINE-CONTAINING COPOLYMER MOLDINGS UNIMATEC CO., LTD. (JP) 2009-01-22 US disclosed
EP-1798252-A1 CROSSLINKED FLUOROCOPOLYMER MOLDINGS Unimatec Co., Ltd. (JP) 2007-06-20 EP disclosed
EP-0421435-B1 Ultrathin membrane of polymethacrylate or polycrotonate and device provided with ultrathin membrane NIPPON OILS & FATS CO LTD (JP) 1996-01-10 EP disclosed
US-5209847-A ULTRATHIN MEMBRANE OF POLYMETHACRYLATE OR POLYCROTONATE AND DEVICE PROVIDED WITH ULTRATHIN MEMBRANE NIPPON OIL AND FATS CO., LTD. (JP) 1993-05-11 US disclosed
EP-0421435-A2 Ultrathin membrane of polymethacrylate or polycrotonate and device provided with ultrathin membrane NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS PHOSPHO1, PGLS, PHYKPL TSHR 4580/4885ALDH1A1 2323/4885MAPK1 3654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.