Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527720 | 0.80 | HRH4 (0.39) | NOS1ALDH1A1MAPK1CNR2PARP1 | |
| SCHEMBL11529766 | 0.77 | HRH4 (0.49) | TDP1 | |
| SCHEMBL2504209 | 0.76 | KDM4E (0.68) | LOXL2CYP3A4MAPTKDM4EMMP8 | |
| SCHEMBL4573652 | 0.76 | ALDH1A1 (0.65) | LOXL2CYP3A4MAPTKDM4EMMP8 | |
| SCHEMBL11529810 | 0.74 | HRH4 (0.59) | — | |
| Hydrochloric Acid SCHEMBL30925271 | 0.74 | KDM4E (0.74) | LOXL2CYP3A4MAPTKDM4EMMP8 | |
| SCHEMBL11533359 | 0.73 | HRH4 (0.62) | — | |
| SCHEMBL11532036 | 0.73 | HRH4 (0.62) | — | |
| SCHEMBL11529676 | 0.73 | HRH4 (0.62) | — | |
| SCHEMBL11532602 | 0.72 | CNR2 (0.56) | LOXL2CYP3A4MAPTKDM4EMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157343-A | Preparation of aromatic diamines | UOP INC. (US) | 1979-06-05 | — | — | US | disclosed |