Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529766 | 0.85 | HRH4 (0.49) | HRH4HRH3LMNASMN1; SMN2MEN1 | |
| SCHEMBL11529810 | 0.82 | HRH4 (0.59) | HRH4HRH3LMNASMN1; SMN2MEN1 | |
| SCHEMBL11529676 | 0.81 | HRH4 (0.62) | HRH4HRH3LMNASMN1; SMN2CHRM2 | |
| SCHEMBL11532036 | 0.81 | HRH4 (0.62) | HRH4HRH3LMNASMN1; SMN2CHRM2 | |
| SCHEMBL11533359 | 0.81 | HRH4 (0.62) | HRH4HRH3LMNASMN1; SMN2CHRM2 | |
| SCHEMBL11529043 | 0.80 | LOXL2 (0.45) | ALDH1A1MAPK1CNR2PARP1NOS1 | |
| SCHEMBL9180552 | 0.78 | LMNA (0.52) | HRH4HRH3LMNASMN1; SMN2MEN1 | |
| SCHEMBL1038338 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPK1CA1 | |
| SCHEMBL11528386 | 0.76 | LMNA (0.58) | LMNASMN1; SMN2MEN1KMT2AGFER | |
| SCHEMBL3969937 | 0.74 | CA1 (0.54) | MEN1KMT2ACYP1A2CYP2C19CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157343-A | Preparation of aromatic diamines | UOP INC. (US) | 1979-06-05 | — | — | US | disclosed |