SCHEMBL11527434

SCHEMBL11527434

CCC(C)c1ccc(C(=O)c2ccccc2F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 1/20 0.45
ABCC8 Q09428 1/20 0.45
KCNJ11 Q14654 1/20 0.45
KCNJ8 Q15842 1/20 0.45
LMNA P02545 3/20 0.44
GAA P10253 1/20 0.44
ESRRA P11474 1/20 0.42
KAT6A Q92794 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 5/20 0.41
TSHR P16473 2/20 0.41
MAPK14 Q16539 1/20 0.41
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALOX15 P16050 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11524017 0.88 ABCC9 (0.43) ABCC9ABCC8KCNJ11KCNJ8LMNA
SCHEMBL11529162 0.84 ESRRA (0.56) ABCC9ABCC8KCNJ11KCNJ8LMNA
SCHEMBL4762195 0.80 ALDH1A1 (0.58) LMNAKDM4EALDH1A1TSHRRAB9A
SCHEMBL9101659 0.80 ALDH1A1 (0.53) LMNAGAAALDH1A1TSHRRAB9A
SCHEMBL10759830 0.80 CES2 (0.62) ABCC9ABCC8KCNJ11KCNJ8LMNA
SCHEMBL6712661 0.79 LMNA (0.45) ABCC9ABCC8KCNJ11KCNJ8LMNA
SCHEMBL5877406 0.79 GRIA4 (0.62) KAT6A
SCHEMBL14366821 0.78 MEN1 (0.67) LMNAKDM4EALDH1A1TSHRRAB9A
SCHEMBL29102705 0.77 CES2 (0.43) ABCC9ABCC8KCNJ11KCNJ8LMNA
SCHEMBL13144208 0.76 MAPT (0.51) LMNAALDH1A1TSHRRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4145444-A 4-BUTYL-BENZOPHENONE KAKEN CHEMICAL CO., LTD. (JP) 1979-03-20 US disclosed
US-4124726-A 2-FLUORO-4'-ALKYLBENZOPHENONE KAKEN CHEMICAL CO., LTD. (JP) 1978-11-07 US disclosed