Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530053 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SLC10A6L3MBTL1KMT2AMAPT | |
| SCHEMBL11529714 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SLC10A6L3MBTL1KMT2AMAPT | |
| SCHEMBL2312520 | 0.79 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL28906801 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SLC10A6L3MBTL1KMT2AMAPT | |
| SCHEMBL1848834 | 0.78 | ALDH1A1 (0.60) | ALDH1A1SLC10A6L3MBTL1KMT2AMAPT | |
| SCHEMBL11530646 | 0.78 | LMNA (0.58) | L3MBTL1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL5804880 | 0.76 | LMNA (0.68) | ALDH1A1L3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL397773 | 0.74 | MAPK1 (0.77) | ALDH1A1L3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL16062225 | 0.74 | PLK1 (0.61) | ALDH1A1SLC10A6KMT2AMAPTMEN1 | |
| SCHEMBL3497986 | 0.74 | MAPT (0.64) | ALDH1A1L3MBTL1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4115574-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |