Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529709 | 0.81 | KMT2A (0.55) | KMT2AMEN1MAPTNPC1KDM4E | |
| SCHEMBL11531552 | 0.81 | ALDH1A1 (0.59) | LMNAKMT2AMEN1MAPTNPC1 | |
| SCHEMBL5804880 | 0.80 | LMNA (0.68) | LMNAL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL11384086 | 0.79 | KMT2A (0.60) | L3MBTL1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL11529437 | 0.78 | ALDH1A1 (0.70) | LMNAL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL2314122 | 0.76 | HSD17B10 (0.68) | LMNAKMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL995011 | 0.76 | NPC1 (0.69) | LMNAL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL538048 | 0.76 | NPC1 (0.63) | LMNAL3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL102285 | 0.76 | KMT2A (0.54) | LMNAL3MBTL1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL11047954 | 0.74 | KMT2A (0.53) | LMNAL3MBTL1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4115574-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |