SCHEMBL11530255

SCHEMBL11530255

COC(=O)c1c([S+]([O-])Cl)c2cc(OC)ccc2n1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
TUBB2A Q13885 1/20 0.45
TUBB8 Q3ZCM7 1/20 0.45
TUBA3E Q6PEY2 1/20 0.45
TUBA1A Q71U36 1/20 0.45
TUBA1C Q9BQE3 1/20 0.45
TUBB6 Q9BUF5 1/20 0.45
TUBB2B Q9BVA1 1/20 0.45
TUBB1 Q9H4B7 1/20 0.45
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11531585 0.88 L3MBTL1 (0.48) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9142952 0.86 L3MBTL1 (0.47) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5659192 0.79 L3MBTL1 (0.55) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9141429 0.75 L3MBTL1 (0.51) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9536705 0.75 KDM4E (0.57) MAPTSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL11533785 0.74 MAPT (0.48) L3MBTL1MAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL11530508 0.73 KDM4E (0.68) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9537227 0.73 L3MBTL1 (0.49) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL11535223 0.73 ALDH1A1 (0.48) L3MBTL1MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL9537603 0.73 PLA2G2A (0.55) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4137313-A ANTICOAGULANTS, ANTIPHLOGISTIC AGENTS BOEHRINGER INGELHEIM GMBH (DE) 1979-01-30 US disclosed