Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528945 | 0.77 | TBXA2R (0.36) | CYP19A1TBXA2RFYNCYP11B2DRD2 | |
| SCHEMBL11529541 | 0.77 | HTR2A (0.41) | CYP19A1TBXA2RFYNCYP11B2DRD2 | |
| SCHEMBL11533272 | 0.76 | TBXA2R (0.46) | TBXA2R | |
| SCHEMBL7862496 | 0.75 | DRD3 (0.60) | FYNDRD2DRD3CYP2D6CYP2C9 | |
| Methyl Alcohol SCHEMBL11526388 | 0.75 | TBXA2R (0.45) | TBXA2R | |
| Methane SCHEMBL11528997 | 0.75 | TBXA2R (0.45) | TBXA2R | |
| SCHEMBL11532857 | 0.75 | ACHE (0.39) | CYP19A1FYNCYP11B2ADRA2APNMT | |
| SCHEMBL31683941 | 0.75 | ACHE (0.39) | CYP19A1FYNCYP11B2ADRA2APNMT | |
| SCHEMBL24214091 | 0.73 | PNMT (0.59) | FYNADRA2APNMTADRA2BADRA2C | |
| SCHEMBL31683944 | 0.73 | SLC6A4 (0.50) | FYNDRD2DRD3ADRA2APNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |