Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 8/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530264 | 0.77 | CYP19A1 (0.36) | TBXA2RDRD2DRD3CYP19A1CYP11B2 | |
| SCHEMBL29237381 | 0.76 | KMT2A (0.41) | TBXA2RDRD2DRD3ENPP2 | |
| SCHEMBL21218921 | 0.72 | ENPP2 (0.40) | DRD2DRD3ENPP2L3MBTL1MMP3 | |
| SCHEMBL11533272 | 0.72 | TBXA2R (0.46) | TBXA2RKDM4ETDP1 | |
| Methyl Alcohol SCHEMBL11526388 | 0.71 | TBXA2R (0.45) | TBXA2RKDM4ETDP1 | |
| Methane SCHEMBL11528997 | 0.71 | TBXA2R (0.45) | TBXA2RKDM4ETDP1 | |
| SCHEMBL11532857 | 0.71 | ACHE (0.39) | CYP19A1CYP11B2FYNADRA2APNMT | |
| SCHEMBL4521078 | 0.71 | ENPP2 (0.39) | ENPP2MMP3KDM4ETDP1ADRA2A | |
| SCHEMBL31683941 | 0.71 | ACHE (0.39) | CYP19A1CYP11B2FYNADRA2APNMT | |
| SCHEMBL1466419 | 0.69 | RXRB (0.40) | ENPP2MMP3KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |