Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525943 | 0.91 | KDM4E (0.54) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL11527640 | 0.86 | LMNA (0.57) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL11527635 | 0.81 | LMNA (0.56) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL11530140 | 0.81 | KDM4E (0.46) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11567781 | 0.80 | ALDH1A1 (0.46) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL19643760 | 0.80 | KMT2A (0.58) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL11529632 | 0.79 | LMNA (0.50) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL11526909 | 0.78 | LMNA (0.46) | KDM4ELMNAALDH1A1SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL11528321 | 0.78 | ALDH1A1 (0.51) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL10827595 | 0.75 | BCHE (0.59) | KDM4ELMNACYP2D6CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140770-A | Benzoylethers and processes for their production | A. NATTERMANN & CIE. GMBH (DE) | 1979-02-20 | — | — | US | disclosed |