Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527635 | 0.93 | LMNA (0.56) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL11530310 | 0.86 | KDM4E (0.48) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL17715387 | 0.83 | KMT2A (0.69) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL11525943 | 0.81 | KDM4E (0.54) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL11529632 | 0.81 | LMNA (0.50) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11528321 | 0.80 | ALDH1A1 (0.51) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL11530140 | 0.79 | KDM4E (0.46) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11567781 | 0.78 | ALDH1A1 (0.46) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL11530069 | 0.76 | PPARA (0.48) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL11525189 | 0.76 | CHRM2 (0.64) | LMNACYP2D6CYP1A2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140770-A | Benzoylethers and processes for their production | A. NATTERMANN & CIE. GMBH (DE) | 1979-02-20 | — | — | US | disclosed |