Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478775 | 0.92 | LMNA (0.61) | LMNASMN1; SMN2NPC1RAB9ACXCR2 | |
| SCHEMBL11533685 | 0.86 | LMNA (0.48) | LMNASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL11535620 | 0.84 | LMNA (0.45) | LMNASMN1; SMN2NPC1RAB9ACXCR2 | |
| SCHEMBL11483687 | 0.83 | LMNA (0.92) | LMNACXCR2HTTKMT2AMEN1 | |
| SCHEMBL11542258 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2NPC1RAB9ACXCR2 | |
| SCHEMBL11530459 | 0.81 | LMNA (0.48) | LMNASMN1; SMN2NPC1RAB9ACXCR2 | |
| SCHEMBL11525613 | 0.80 | LMNA (0.46) | LMNASMN1; SMN2NPC1RAB9ACXCR2 | |
| SCHEMBL11534547 | 0.80 | LMNA (1.00) | LMNASMN1; SMN2CXCR2L3MBTL1HTT | |
| SCHEMBL11523831 | 0.78 | LMNA (0.45) | LMNASMN1; SMN2NPC1RAB9ACXCR2 | |
| SCHEMBL11483627 | 0.78 | LMNA (0.45) | LMNASMN1; SMN2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153611-A | ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-05-08 | — | — | US | disclosed |
| US-4150035-A | ANIMAL CROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-04-17 | — | — | US | disclosed |