Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637229 | 0.85 | NOX1 (0.35) | NOX1PTGS2CHRM1 | |
| SCHEMBL11532653 | 0.79 | DRD2 (0.40) | CHRM1 | |
| SCHEMBL11532011 | 0.76 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL6814192 | 0.75 | LMNA (0.39) | PTGS2CHRM1 | |
| SCHEMBL11634008 | 0.72 | HRH4 (0.53) | CHRM1 | |
| SCHEMBL11635535 | 0.71 | DRD2 (0.38) | CHRM1 | |
| SCHEMBL11531278 | 0.70 | MAPT (0.38) | NOX1CHRM1 | |
| SCHEMBL11529621 | 0.70 | NOX1 (0.40) | NOX1PTGS2 | |
| SCHEMBL11630707 | 0.70 | CHRM1 (0.41) | CHRM1 | |
| SCHEMBL11633472 | 0.70 | CHRM1 (0.40) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115574-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |