Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539178 | 0.92 | ALDH1A1 (0.47) | HPGDALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11533466 | 0.89 | MAPT (0.40) | CES2HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11534227 | 0.88 | LMNA (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL11534215 | 0.87 | LMNA (0.40) | CES2HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11531850 | 0.86 | LMNA (0.39) | ALDH1A1MAPTSMN1; SMN2LMNAKCNK3 | |
| SCHEMBL11533358 | 0.84 | CYP19A1 (0.43) | CES2HPGDALDH1A1MAPTLMNA | |
| SCHEMBL11534789 | 0.84 | ALDH1A1 (0.39) | HPGDALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11534023 | 0.84 | CYP19A1 (0.46) | HPGDALDH1A1MAPTLMNANPC1 | |
| SCHEMBL11534117 | 0.82 | SMN1; SMN2 (0.41) | HPGDALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11530465 | 0.82 | ALDH1A1 (0.42) | HPGDALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |