Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531998 | 0.89 | CES2 (0.42) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11532706 | 0.88 | LMNA (0.49) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL11534215 | 0.88 | LMNA (0.40) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11534789 | 0.85 | ALDH1A1 (0.39) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11539178 | 0.84 | ALDH1A1 (0.47) | MAPTHPGDALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11533025 | 0.83 | CYP19A1 (0.46) | MAPTLMNAKMT2ACYP3A4 | |
| SCHEMBL11533669 | 0.82 | LMNA (0.43) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11536312 | 0.81 | TSHR (0.44) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL11533530 | 0.79 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL11533863 | 0.79 | LMNA (0.40) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |