Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534227 | 0.89 | LMNA (0.47) | CYP19A1LMNACES1ALDH1A1GAA | |
| SCHEMBL11536284 | 0.89 | LMNA (0.37) | CYP19A1LMNACES1ALDH1A1GAA | |
| SCHEMBL11531850 | 0.88 | LMNA (0.39) | LMNACES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11534440 | 0.87 | LMNA (0.43) | CYP19A1LMNACES1CES2KMT2A | |
| SCHEMBL11531974 | 0.86 | CYP19A1 (0.42) | CYP19A1LMNACES1CES2KMT2A | |
| SCHEMBL11530465 | 0.86 | ALDH1A1 (0.42) | CYP19A1LMNACES1KMT2ANPC1 | |
| SCHEMBL11538107 | 0.85 | CYP19A1 (0.41) | CYP19A1LMNACES1CES2KMT2A | |
| SCHEMBL11534023 | 0.85 | CYP19A1 (0.46) | CYP19A1LMNACES1KMT2ANPC1 | |
| SCHEMBL11531901 | 0.85 | SMN1; SMN2 (0.46) | CYP19A1LMNACES1CES2KMT2A | |
| SCHEMBL11531998 | 0.84 | CES2 (0.42) | LMNACES2KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |