SCHEMBL11533254

SCHEMBL11533254

COC(=O)C(C(=O)OC)=C(N)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
PKM P14618 1/20 0.35
GAA P10253 2/20 0.33
EZH2 Q15910 1/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11529927 0.82 ALDH1A1 (0.36) KMT2AMEN1GAAPOLBRECQL
SCHEMBL11526285 0.80 ATM (0.35) L3MBTL1ATMKMT2AMEN1PKM
SCHEMBL11532124 0.75 ALDH1A1 (0.34) KMT2AMEN1GAAPOLB
SCHEMBL11528566 0.75 GAA (0.50) L3MBTL1KMT2AMEN1PKMGAA
SCHEMBL27796646 0.75 ATM (0.37) L3MBTL1ATMKMT2AMEN1PKM
SCHEMBL10084365 0.74 CHRNB2 (0.44) L3MBTL1ATMKMT2AMEN1PKM
SCHEMBL5087932 0.73 GAA (0.37) L3MBTL1ATMKMT2AGAAEZH2
SCHEMBL28498913 0.71 MEN1 (0.37) L3MBTL1ATMKMT2AMEN1PKM
Methyl Carbamate SCHEMBL9813667 0.71 ATM (0.39) L3MBTL1ATMKMT2AMEN1PKM
SCHEMBL19551259 0.69 ATM (0.45) L3MBTL1ATMKMT2AMEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4140673-A REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS BAYER AKTIENGESELLSCHAFT (DE) 1979-02-20 US disclosed