Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527873 | 0.87 | MAPK1 (0.40) | L3MBTL1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11499291 | 0.71 | SMN1; SMN2 (0.58) | L3MBTL1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28438225 | 0.71 | SMN1; SMN2 (0.50) | L3MBTL1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11533788 | 0.71 | MT-CO2 (0.45) | L3MBTL1HPGDPTGS2PSEN1PSEN2 | |
| SCHEMBL9289868 | 0.70 | PTGS2 (0.66) | L3MBTL1PTGS2TSHRTDP1MAPT | |
| SCHEMBL11717547 | 0.70 | PTGS2 (0.50) | L3MBTL1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9239307 | 0.70 | PTGS2 (0.66) | L3MBTL1PTGS2TSHRTDP1MAPT | |
| SCHEMBL28968063 | 0.70 | L3MBTL1 (0.52) | L3MBTL1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13156984 | 0.70 | TSHR (0.54) | L3MBTL1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL15896735 | 0.70 | TSHR (0.54) | L3MBTL1NPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |