Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | CDC42 | P60953 | 1/20 | 0.35 |
| ▸ | RAC1 | P63000 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526124 | 0.86 | MT-CO2 (0.41) | MT-CO2PTGS2PTGS1HPGDTDP1 | |
| SCHEMBL11529146 | 0.83 | PTGS2 (0.47) | PTGS2PTGS1KMT2AMEN1AKR1C3 | |
| SCHEMBL11535068 | 0.76 | PTGS2 (0.48) | MT-CO2PTGS2PTGS1HPGDTDP1 | |
| SCHEMBL11529076 | 0.75 | MT-CO2 (0.44) | MT-CO2PTGS2PTGS1HPGDTDP1 | |
| SCHEMBL11527873 | 0.74 | MAPK1 (0.40) | MT-CO2TDP1L3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10405724 | 0.74 | MT-CO2 (0.43) | MT-CO2PTGS2PTGS1HPGDTDP1 | |
| SCHEMBL11682946 | 0.72 | RAB9A (0.44) | MT-CO2PTGS2PTGS1KDM4EMAPT | |
| SCHEMBL11679644 | 0.72 | TDP1 (0.51) | PTGS2PTGS1KDM4EMAPTHPGD | |
| SCHEMBL11531372 | 0.72 | MT-CO2 (0.42) | MT-CO2PTGS2PTGS1HPGDTDP1 | |
| SCHEMBL11010931 | 0.72 | MT-CO2 (0.42) | MT-CO2PTGS2PTGS1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |