Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637060 | 0.94 | CNR2 (0.44) | LMNAALDH1A1MAPTNPSR1MCOLN3 | |
| SCHEMBL11634802 | 0.94 | CNR2 (0.44) | LMNAALDH1A1MAPTNPSR1MCOLN3 | |
| SCHEMBL11637629 | 0.81 | NPC1 (0.43) | LMNAALDH1A1MAPTNPSR1MCOLN3 | |
| SCHEMBL11635413 | 0.81 | NPC1 (0.43) | LMNAALDH1A1MAPTNPSR1MCOLN3 | |
| SCHEMBL11637786 | 0.79 | BCL2L1 (0.37) | LMNAALDH1A1MAPTNPSR1MCOLN3 | |
| SCHEMBL11636835 | 0.79 | ALDH1A1 (0.57) | LMNAALDH1A1MAPTNPSR1MCOLN3 | |
| SCHEMBL13991203 | 0.78 | CNR2 (0.65) | LMNAALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL11536142 | 0.78 | MAPT (0.51) | ALDH1A1MAPTKDM4EHSD17B10POLB | |
| SCHEMBL13617372 | 0.76 | MEN1 (0.64) | LMNAALDH1A1MAPTNPSR1MCOLN3 | |
| SCHEMBL11636106 | 0.76 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132795-A | Benzenesulfonyl ureas and their use for the treatment of diabetes mellitus | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |