Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637060 | 1.00 | CNR2 (0.44) | CNR2KDM4EUSP2ALDH1A1NPSR1 | |
| SCHEMBL11534161 | 0.94 | LMNA (0.48) | CNR2KDM4EUSP2ALDH1A1NPSR1 | |
| SCHEMBL11635413 | 0.87 | NPC1 (0.43) | CNR2KDM4EUSP2ALDH1A1NPSR1 | |
| SCHEMBL11637629 | 0.87 | NPC1 (0.43) | CNR2KDM4EUSP2ALDH1A1NPSR1 | |
| SCHEMBL11636835 | 0.85 | ALDH1A1 (0.57) | CNR2KDM4EUSP2ALDH1A1NPSR1 | |
| SCHEMBL11637786 | 0.77 | BCL2L1 (0.37) | KDM4EUSP2ALDH1A1NPSR1LMNA | |
| SCHEMBL11536142 | 0.75 | MAPT (0.51) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL11634559 | 0.75 | KDM4E (0.77) | KDM4EUSP2ALDH1A1NPSR1LMNA | |
| SCHEMBL11637219 | 0.75 | KDM4E (0.77) | KDM4EUSP2ALDH1A1NPSR1LMNA | |
| SCHEMBL11637352 | 0.75 | KDM4E (0.43) | CNR2KDM4EALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108630-A | 1-Alkylpyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4038065-A | 1-ALKYLPYRID-2-ONE | ROHM AND HAAS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |