Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609712 | 0.85 | NOTUM (0.57) | MAPTSMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL11611300 | 0.78 | ERCC5 (0.55) | MAPTSMN1; SMN2KDM4EALDH1A1FEN1 | |
| SCHEMBL11534161 | 0.78 | LMNA (0.48) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL11435796 | 0.77 | KMT2A (0.49) | MAPTSMN1; SMN2KDM4EALDH1A1TAAR1 | |
| SCHEMBL11610760 | 0.76 | ERCC5 (0.53) | MAPTKDM4EALDH1A1RAB9AHSD17B10 | |
| SCHEMBL13617372 | 0.76 | MEN1 (0.64) | MAPTSMN1; SMN2KDM4EALDH1A1TAAR1 | |
| SCHEMBL11611290 | 0.75 | TP53 (0.48) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL11637060 | 0.75 | CNR2 (0.44) | MAPTKDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL11634802 | 0.75 | CNR2 (0.44) | MAPTKDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL11610226 | 0.75 | GAA (0.52) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132795-A | Benzenesulfonyl ureas and their use for the treatment of diabetes mellitus | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |