Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528029 | 0.84 | SSTR4 (0.48) | MAPTPOLBNPC1CASP3RAB9A | |
| SCHEMBL11529949 | 0.79 | CES2 (0.53) | MAPTL3MBTL1POLBNPC1RAB9A | |
| SCHEMBL11528361 | 0.79 | PPARA (0.47) | MAPTL3MBTL1POLBNPC1RAB9A | |
| SCHEMBL11528571 | 0.78 | SSTR4 (0.47) | MAPTL3MBTL1NR4A2CASP3SENP7 | |
| SCHEMBL11735204 | 0.78 | MRGPRX4 (0.47) | TDP1RXRARXRBPOLBNPC1 | |
| SCHEMBL11530819 | 0.78 | MAP4K4 (0.47) | MAPTTDP1L3MBTL1NR4A2POLB | |
| SCHEMBL11526889 | 0.77 | RXRA (0.50) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL11735211 | 0.75 | RXRA (0.44) | MAPTTDP1L3MBTL1RXRARXRB | |
| SCHEMBL757100 | 0.74 | CES1 (0.50) | MAPTTDP1POLBCES1LMNA | |
| SCHEMBL11731959 | 0.73 | SSTR4 (0.50) | MAPTTDP1L3MBTL1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065503-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1977-12-27 | — | — | US | claimed |
| US-4175138-A | α-Alkyl-p-phenoxy benzyl alcohols, compositions and treating lipidemia | SANDOZ, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4085149-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4065503-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-3997567-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1976-12-14 | — | — | US | disclosed |
| US-3962459-A | Lipidemia treatment with p-phenoxy-alkylphenone compositions | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | disclosed |