Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528029 | 0.89 | SSTR4 (0.48) | SSTR4PPARAMAPK1CASP3SENP7 | |
| SCHEMBL11528361 | 0.86 | PPARA (0.47) | PPARALMNAL3MBTL1MAOBDGAT1 | |
| SCHEMBL11529949 | 0.86 | CES2 (0.53) | PPARALMNAMAPK1L3MBTL1KDM4E | |
| SCHEMBL11735204 | 0.85 | MRGPRX4 (0.47) | PPARALMNAALDH1A1MAOBDGAT1 | |
| SCHEMBL11530819 | 0.85 | MAP4K4 (0.47) | SSTR4PPARAL3MBTL1NR4A2KDM4E | |
| SCHEMBL21748731 | 0.82 | DGAT1 (0.52) | SSTR4PPARANR4A2KDM4EMAOB | |
| SCHEMBL10556663 | 0.79 | SSTR4 (0.52) | SSTR4LMNANR4A2KDM4EALDH1A1 | |
| SCHEMBL11735211 | 0.79 | RXRA (0.44) | SSTR4PPARACASP3SENP7L3MBTL1 | |
| SCHEMBL11534162 | 0.78 | MAPT (0.44) | PPARALMNAMAPK1CASP3SENP7 | |
| SCHEMBL11731959 | 0.77 | SSTR4 (0.50) | SSTR4L3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175138-A | α-Alkyl-p-phenoxy benzyl alcohols, compositions and treating lipidemia | SANDOZ, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4085149-A | HYPOLIPIDEMIC | SANDOZ, INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4065503-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-3962459-A | Lipidemia treatment with p-phenoxy-alkylphenone compositions | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | disclosed |