Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16170237 | 0.93 | POLB (0.45) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL11538334 | 0.80 | CES1 (0.53) | MAPTLRRK2 | |
| SCHEMBL11539506 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTHPGDLRRK2 | |
| SCHEMBL16170247 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL11536434 | 0.75 | MAOA (0.47) | ALDH1A1KDM4EHPGDHSD17B10ACVR1 | |
| SCHEMBL24649691 | 0.74 | CYP1A2 (0.46) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL16170250 | 0.74 | KDM4E (0.47) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL15219327 | 0.74 | ROS1 (0.54) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL16163174 | 0.74 | PDE7A (0.62) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL16170245 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154731-A | ANTISECRETORY AGENTS, ANTIINFLAMMATORY AGENTS, ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-05-15 | — | — | US | disclosed |
| US-4105670-A | ANTISECRETORY, ANTIINFLAMMATORY, ANALGESIC, DECARBOXYLATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-08-08 | — | — | US | disclosed |