Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ROS1 | P08922 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534209 | 0.93 | ALDH1A1 (0.47) | POLBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL16163174 | 0.81 | PDE7A (0.62) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL16170247 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL16163017 | 0.77 | PDE7A (0.54) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11538334 | 0.74 | CES1 (0.53) | MAPTLRRK2PDE7A | |
| SCHEMBL30740464 | 0.74 | CA1 (0.42) | ALDH1A1MAPTKMT2ALRRK2CA1 | |
| SCHEMBL11539506 | 0.73 | ALDH1A1 (0.57) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL16170250 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL14773646 | 0.71 | CA1 (0.44) | KDM4EALDH1A1HTTCDK5PDE7A | |
| SCHEMBL16170245 | 0.70 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145364-B2 | Synthesis of psuedo indoxyl derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-09-29 | — | — | US | disclosed |
| US-20140309434-A1 | SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309434-A1 | SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES | IPO4, IPO11, IDO2 | POLB 2683/4885KDM4E 1188/4885ALDH1A1 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.