Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31394896 | 0.79 | TGM2 (0.50) | ALDH1A1MAPTKDM4ELRRK2CA1 | |
| SCHEMBL11534209 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL16170250 | 0.79 | KDM4E (0.47) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL16170245 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL16163180 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHPGDLRRK2 | |
| SCHEMBL16170237 | 0.77 | POLB (0.45) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL13469502 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10ACVR1 | |
| SCHEMBL7170898 | 0.73 | CSNK1G1 (0.45) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL16170243 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL29657257 | 0.69 | ROS1 (0.67) | ALDH1A1MAPTROS1CDK5ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145364-B2 | Synthesis of psuedo indoxyl derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-09-29 | — | — | US | disclosed |
| US-20140309434-A1 | SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309434-A1 | SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES | IPO4, IPO11, IDO2 | ALDH1A1 2135/4885MAPT 369/4885KDM4E 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.