Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808497 | 0.84 | MEN1 (0.41) | MEN1KMT2AALDH1A1TSHRTP53 | |
| SCHEMBL17064719 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1TSHRCES2 | |
| SCHEMBL14454720 | 0.74 | CA1 (0.47) | KMT2AALDH1A1TSHRDAONAPRT | |
| SCHEMBL4139139 | 0.73 | NPSR1 (0.44) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4821584 | 0.72 | MEN1 (0.42) | MEN1KMT2AALDH1A1TSHRTP53 | |
| Terephthalic Acid SCHEMBL28348573 | 0.72 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1TSHRSRD5A2 | |
| SCHEMBL7523648 | 0.72 | GAA (0.45) | MEN1KMT2AALDH1A1TSHRPKM | |
| SCHEMBL20677772 | 0.72 | HSP90AA1 (0.58) | ALDH1A1TSHRDAONAPRTCES2 | |
| Benzoic Acid SCHEMBL2762272 | 0.71 | TSHR (0.74) | MEN1KMT2AALDH1A1TSHRDAO | |
| Benzoic Acid SCHEMBL578126 | 0.71 | TSHR (0.74) | MEN1KMT2AALDH1A1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140712-A | 20-Hydroxy-prostaglandins | ONO PHARMACEUTICAL COMPANY (JP) | 1979-02-20 | — | — | US | disclosed |
| US-4117119-A | 15-CYCLOBUTYL-PROSTAGLANDINS | ONO PHARMACEUTICAL COMPANY (JP) | 1978-09-26 | — | — | US | disclosed |
| US-4045468-A | GASTRIC ULCERS | ONO PHARMACEUTICAL COMPANY (JA) | 1977-08-30 | — | — | US | disclosed |
| US-4024174-A | MEDICINE | ONO PHARMACEUTICAL COMPANY (JA) | 1977-05-17 | — | — | US | disclosed |
| US-3966792-A | Prostaglandin compounds | ONO PHARMACEUTICAL CO., LTD. (JA) | 1976-06-29 | — | — | US | disclosed |