Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190077 | 0.83 | GAA (0.41) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL808497 | 0.81 | MEN1 (0.41) | GAAHSP90AA1TSHRALDH1A1MEN1 | |
| SCHEMBL11769205 | 0.79 | TDP1 (0.36) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL4139139 | 0.79 | NPSR1 (0.44) | HSP90AA1CFTRTSHRUSP2ALDH1A1 | |
| SCHEMBL4821584 | 0.77 | MEN1 (0.42) | GAATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9802194 | 0.77 | AOX1 (0.47) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL15187709 | 0.77 | ALDH1A1 (0.41) | CA2TDP1ALOX15ALDH1A1 | |
| SCHEMBL18121489 | 0.76 | CYP3A4 (0.33) | HSP90AA1CFTRTSHRUSP2ALDH1A1 | |
| SCHEMBL8987951 | 0.76 | MEN1 (0.41) | MEN1KMT2APKM | |
| SCHEMBL19634601 | 0.76 | HTT (0.44) | GAAHSP90AA1CFTRTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0872466-B1 | Process for the synthesis of 1,7-diaryl or 1,7-heteroarylheptan-4-ols and synthetic intermediates | FABBRICA ITALIANA SINTETICI SPA (IT) | 2002-01-30 | — | — | EP | disclosed |
| US-5973157-A | Process for the synthesis of 1,7-diarly or heteroaryl-heptane-4-ols and new synthetic intermediates | F.I.S. FABBRICA ILTALIANA SINTETICI S.P.A. (IT) | 1999-10-26 | — | — | US | disclosed |
| EP-0872466-A1 | Process for the synthesis of 1,7-diaryl or 1,7-heteroarylheptan-4-ols and synthetic intermediates | F.I.S. FABBRICA ITALIANA SINTETICI S.p.A. (IT) | 1998-10-21 | — | — | EP | disclosed |