Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD1 | P21728 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28156705 | 0.81 | ADRB2 (0.68) | MTNR1AMTNR1BHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL10772911 | 0.80 | ADRB2 (0.66) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL8055391 | 0.77 | SIGMAR1 (0.55) | MTNR1AMTNR1BHTR1AADRA1DADRA1A | |
| SCHEMBL6192822 | 0.77 | MTNR1A (0.62) | MTNR1AMTNR1BHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9064978 | 0.76 | MTNR1A (0.50) | MTNR1AMTNR1BHTR1AADRA1DADRA1A | |
| SCHEMBL10585937 | 0.76 | ADRB2 (0.61) | MTNR1AMTNR1BHTR1AADRA1DADRA1A | |
| SCHEMBL1592409 | 0.75 | CA12 (0.68) | MTNR1AMTNR1BHTR1AADRA1DADRA1A | |
| SCHEMBL8001439 | 0.75 | MTNR1A (0.60) | MTNR1AMTNR1BHTR1AADRA1DADRA1A | |
| SCHEMBL5819256 | 0.75 | LMNA (0.56) | MTNR1AMTNR1BHTR1AADRA1DADRA1A | |
| SCHEMBL5694627 | 0.75 | MTNR1A (0.60) | MTNR1AMTNR1BHTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152438-A | HYPOTENSIVE AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1979-05-01 | — | — | US | disclosed |