SCHEMBL11535386

SCHEMBL11535386

CCC1(C)CC(OC(=O)Cc2ccccc2)C(C)C(C)(CC)N1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 9/20 0.42
TSHR P16473 1/20 0.39
CYP17A1 P05093 2/20 0.38
FAAH O00519 1/20 0.35
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.34
PAM P19021 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11531922 0.84 ALDH1A1 (0.42) TSHRALDH1A1MEN1KMT2A
SCHEMBL11533627 0.81
SCHEMBL11447573 0.79 HTT (0.31)
SCHEMBL11536762 0.79 GAA (0.41) TSHRALDH1A1MEN1KMT2AMAPK1
SCHEMBL11533957 0.79 PRKCA (0.36)
SCHEMBL11532198 0.78
SCHEMBL11531928 0.78 LMNA (0.48) TSHRALDH1A1GAA
SCHEMBL11620440 0.78 PRKCA (0.38) MEN1KMT2A
SCHEMBL11471192 0.78 EPHX2 (0.40) ALDH1A1MEN1KMT2AGAA
SCHEMBL11535607 0.78 GAA (0.40) TSHRALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141883-A Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives SANKYO COMPANY, LIMITED (JP) 1979-02-27 US disclosed
US-4075165-A 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed