Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 5/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536497 | 0.83 | CYP19A1 (0.40) | DAOCYP19A1 | |
| SCHEMBL11542166 | 0.83 | GAA (0.45) | GAADAOMAPT | |
| SCHEMBL11540707 | 0.82 | DAO (0.39) | DAOMAPTKDM4E | |
| SCHEMBL3165240 | 0.78 | EPHX2 (0.46) | GAAPOLBERCC1ERCC4DAO | |
| SCHEMBL11538902 | 0.70 | ACP3 (0.39) | GAADAOMAPTKDM4EROCK2 | |
| SCHEMBL2489611 | 0.69 | IDO1 (0.50) | GAAPOLBCYP19A1 | |
| SCHEMBL11537810 | 0.69 | NR3C1 (0.44) | GAAMAPTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30821590 | 0.68 | IDO1 (0.39) | GAAPOLBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL31005301 | 0.64 | CYP19A1 (0.36) | GAACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11537244 | 0.63 | BRD4 (0.43) | DAOMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |